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CEPHADOL TABLET
 
Cephadol Tablet

COMPOSITION:

Each tablet contains 25mg of Difenidol HCI (Chemical name : 1,1 - diphenyl - 4 - diperidino -1- butanol hydrochloride)

Difenidol is a compound NOT related to the antihistamines, phenothiazines, barbiturates, or other agents with antivertigo or antiemetic action.

 

THERAPEUTIC PROPERTIES:

  1. Improvement of circulation in vertebral basilar arteries.
   

Cephadol releases contraction of vertebral basilar arteries shown in the symptom of vertigo to improve the blood stream and keeps the balance of vertebral artery blood stream on both side.

As it works selectively against contraction of blood vessel, it would not cause  so-called intracerebral steal syndrome and gives almost no effect on the total blood pressure.

     
  2. Blocking effect against vestibular abnormal stimulation.
    Cephadol blocks abnormal stimulation at the levels of vestibular nucleus and hypothalamus. The above blocking actions are specific, almost have no influence on the upper central nervous system, being by far different from antihistaminics and sedatives.
     
  3. Suppression of nausea and vomiting at the chemotrigger zone.
    Cephadol is a potent anti-emetic agent.

 

INDICATIONS:

  1. Vertigo associated with inner ear disturbances (labyrinthitis, vestibular neuronitis)

  2. Meniere's disease

  3. Vertigo associated with vertebral arteries circulation insufficiency

  4. Nausea and vomiting


DOSAGE AND ADMINISTRATION:
For adults, usually 1 - 2 tablets, 3 times daily, preferably after meals. This dose should be adjusted depending on the age and symptoms.

 

ADVERSE REACTIONS:

Reduce or pause when thirst, heartburn, mydriasis, palpitation, etc are observed by the administration of the drug. In addition to the above, pay attention to occurrences of rash, discomfort feeling, heavy feeling in head and drowsiness.

 

CONTRAINDICATIONS:

  1. Patients with serious renal functional disorders.

  2. Patients with a history of hypersensitivity to this drug



USAGE IN PREGNANCY:

As safety of Cephadol in pregnancy has not been established, it should not be administered in pregnant women or women suspected of being pregnant.

 

DRUG INTERACTIONS:

None known.

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         References: Please contact us for further information at mgnt@wellchem.com